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Efficacy of Fecal Microbiota Transplantation for Clostridium difficile Infection in Children

Nicholson MR, Mitchell PD, Alexander E, Ballal S, Bartlett M, Becker P, Davidovics Z, Docktor M, Dole M, Felix G, Gisser J, Hourigan SK, Jensen MK, Kaplan JL, Kelsen J, Kennedy M, Khanna S, Knackstedt E, Leier M, Lewis J, Lodarek A, Michail S, Oliva-Hemker M, Patton T, Queliza K, Russell GH, Singh N, Solomon A, Suskind DL, Werlin S, Kellermayer R, Kahn SA. Efficacy of Fecal Microbiota Transplantation for Clostridium difficile Infection in Children. Clin Gastroenterol Hepatol. 2020 Mar;18(3):612-619.e1. doi: 10.1016/j.cgh.2019.04.037. Epub 2019 Apr 19. PMID: 31009795; PMCID: PMC7549313.

Outcomes of Fecal Microbiota Transplantation in Patients With Inflammatory Bowel Diseases and Recurrent Clostridioides difficile Infection

Allegretti, J., Kelly, C., Grinspan, A., Mullish, B., Kassam, Z., & Fischer, M. (2020). Outcomes of Fecal Microbiota Transplantation in Patients With Inflammatory Bowel Diseases and Recurrent Clostridioides difficile Infection. Gastroenterology, 159(5), 1982-1984. doi: 10.1053/j.gastro.2020.07.045

Prevalence and impact of Clostridioides difficile infection among hospitalized patients with coranavirus disease 2019

Allegretti, J., Nije, C., McClure, E., Redd, W., Wong, D., & Zhou, J. et al. (2021). Prevalence and impact of Clostridioides difficile infection among hospitalized patients with coranavirus disease 201 9. JGH Open, 5(5), 622-625. doi: 10.1002/jgh3.12497

Clostridioides difficile Infection in Pediatric Inflammatory Bowel Disease: A Clinician’s Dilemma

Conrad MA, Kelsen JR. Clostridioides difficile Infection in Pediatric Inflammatory Bowel Disease: A Clinician’s Dilemma. J Pediatric Infect Dis Soc. 2021 Aug 3:piab069. doi: 10.1093/jpids/piab069. Epub ahead of print. PMID: 34343321.

Heterogeneity of Randomized Controlled Trials of Fecal Microbiota Transplantation in Recurrent Clostridioides difficile Infection

Feuerstadt P, Aroniadis OC, Svedlund FL, Garcia M, Stong L, Boules M, Khanna S. Heterogeneity of Randomized Controlled Trials of Fecal Microbiota Transplantation in Recurrent Clostridioides difficile Infection. Dig Dis Sci. 2021 Jul 18. doi: 10.1007/s10620-021-07141-9. Epub ahead of print. PMID: 34275058.

Cost-effectiveness analysis of sequential fecal microbiota transplantation for fulminant Clostridioides difficile infection

Gupta S, Zhu J, McCarty TR, Pruce J, Kassam Z, Kelly C, Fischer M, Allegretti JR. Cost-effectiveness analysis of sequential fecal microbiota transplantation for fulminant Clostridioides difficile infection. J Gastroenterol Hepatol. 2021 Sep;36(9):2432-2440. doi: 10.1111/jgh.15483. Epub 2021 Mar 17. PMID: 33682170.

Hospital-onset Clostridioides difficile infections during the COVID-19 pandemic

Luo Y, Grinspan LT, Fu Y, Adams-Sommer V, Willey DK, Patel G, Grinspan AM. Hospital-onset Clostridioides difficile infections during the COVID-19 pandemic. Infect Control Hosp Epidemiol. 2021 Sep;42(9):1165-1166. doi: 10.1017/ice.2020.1223. Epub 2020 Sep 23. PMID: 32962772; PMCID: PMC7545245.

The contribution of bile acid metabolism to the pathogenesis of Clostridioides difficile infection

Mullish, B., & Allegretti, J. (2021). The contribution of bile acid metabolism to the pathogenesis of Clostridioides difficile infection. Therapeutic Advances In Gastroenterology, 14, 175628482110177. doi: 10.1177/17562848211017725

Management of Severe and Severe/Complicated Clostridoides difficile Infection using Sequential Fecal Microbiota Transplant by Retention Enema

Rupawala AH, Gachette D, Bakhit M, Jimoh L, Kelly CR. Management of Severe and Severe/Complicated Clostridoides difficile Infection using Sequential Fecal Microbiota Transplant by Retention Enema. Clin Infect Dis. 2021 Jan 21:ciab041. doi: 10.1093/cid/ciab041. Epub ahead of print. PMID: 33476379.

Fecal Microbiota Transplantation for Severe or Fulminant Clostridioides difficile Infection

Song YN, Yang DY, Veldhuyzen van Zanten S, Wong K, McArthur E, Song CZ, Ianiro G, Cammarota G, Kelly C, Fischer M, Russell L, Kao D. Fecal Microbiota Transplantation for Severe or Fulminant Clostridioides difficile Infection: Systematic Review and Meta-analysis. J Can Assoc Gastroenterol. 2021 Jul 23;5(1):e1-e11. doi: 10.1093/jcag/gwab023. PMID: 35118227; PMCID: PMC8806043.

Systematic Review with Meta-Analysis: Fecal Microbiota Transplantation for Severe or Fulminant Clostridioides difficile

Tixier EN, Verheyen E, Luo Y, Grinspan LT, Du CH, Ungaro RC, Walsh S, Grinspan AM. Systematic Review with Meta-Analysis: Fecal Microbiota Transplantation for Severe or Fulminant Clostridioides difficile. Dig Dis Sci. 2021 Mar 22. doi: 10.1007/s10620-021-06908-4. Epub ahead of print. PMID: 33748913.

Treatment of Recurrent Clostridium difficile Infection in an Immunocompromised Patient with Severe Neutropenia Not Responding to Standard Therapy

AlQahtani, H., Baloch, S., & Tabb, D. (2020). Treatment of Recurrent Clostridium difficile Infection in an Immunocompromised Patient with Severe Neutropenia Not Responding to Standard Therapy. Case Reports In Infectious Diseases, 2020, 1-4. doi:10.1155/2020/3089023

Fecal Microbiota Transplant Decreases Mortality in Patients with Refractory Severe or Fulminant Clostridioides difficile Infection

Cheng, Y., Phelps, E., Nemes, S., Rogers, N., Sagi, S., & Bohm, M. et al. (2020). Fecal Microbiota Transplant Decreases Mortality in Patients with Refractory Severe or Fulminant Clostridioides difficile Infection. Clinical Gastroenterology And Hepatology. doi:10.1016/j.cgh.2019.12.029

Understanding the mechanisms of efficacy of fecal microbiota transplant in treating recurrent Clostridioides difficile infection and beyond: the contribution of gut microbial-derived metabolites

Martinez-Gili, L., McDonald, J., Liu, Z., Kao, D., Allegretti, J., & Monaghan, T. et al. (2020). Understanding the mechanisms of efficacy of fecal microbiota transplant in treating recurrent Clostridioides difficile infection and beyond: the contribution of gut microbial-derived metabolites. Gut Microbes, 12(1), 1810531. doi: 10.1080/19490976.2020.1810531

Fecal microbiota transplantation “donor effects” are not clinically relevant for Clostridioides difficile infection

Olesen SW. Fecal microbiota transplantation “donor effects” are not clinically relevant for Clostridioides difficile infection. Gastroenterology. 2020 Dec 30:S0016-5085(20)35620-1. doi: 10.1053/j.gastro.2020.12.057. Epub ahead of print. PMID: 33387515.

Long-Term Efficacy and Safety of Fecal Microbiota Transplantation for Treatment of Recurrent Clostridioides difficile Infection

Perler, B., Chen, B., Phelps, E., Allegretti, J., Fischer, M., & Ganapini, V. et al. (2020). Long-Term Efficacy and Safety of Fecal Microbiota Transplantation for Treatment of Recurrent Clostridioides difficile Infection. Journal Of Clinical Gastroenterology, 1. doi:10.1097/mcg.0000000000001281

Fecal Microbiota Transplantation Capsules with Targeted Colonic Versus Gastric Delivery in Recurrent Clostridium difficile Infection: A Comparative Cohort Analysis of High and Lose Dose

Allegretti, J., Fischer, M., Sagi, S., Bohm, M., Fadda, H., & Ranmal, S. et al. (2018). Fecal Microbiota Transplantation Capsules with Targeted Colonic Versus Gastric Delivery in Recurrent Clostridium difficile Infection: A Comparative Cohort Analysis of High and Lose Dose. Digestive Diseases And Sciences, 64(6), 1672-1678. doi:10.1007/s10620-018-5396-6

Clinical Predictors of Recurrence After Primary Clostridioides difficile Infection: A Prospective Cohort Study

Allegretti, J., Marcus, J., Storm, M., Sitko, J., Kennedy, K., Gerber, G., & Bry, L. (2019). Clinical Predictors of Recurrence After Primary Clostridioides difficile Infection: A Prospective Cohort Study. Digestive Diseases And Sciences. doi:10.1007/s10620-019-05900-3

Bezlotoxumab use as adjunctive therapy with the third fecal microbiota transplant in refractory recurrent Clostridium difficilecolitis; a case report and concise literature review

Kaako, A., Al-Amer, M., & Abdeen, Y. (2019). Bezlotoxumab use as adjunctive therapy with the third fecal microbiota transplant in refractory recurrent Clostridium difficile colitis; a case report and concise literature review. Anaerobe, 55, 112-116. doi:10.1016/j.anaerobe.2018.11.010

Patients Eligible for Trials of Microbe-based Therapeutics do not Represent the Population With Recurrent Clostridioides difficile Infection

Kelly, C., Fischer, M., Grinspan, A., & Allegretti, J. (2019). Patients Eligible for Trials of Microbe-based Therapeutics do not Represent the Population With Recurrent Clostridioides difficile Infection. Clinical Gastroenterology And Hepatology. doi:10.1016/j.cgh.2019.06.034

Faecal microbiota transplant decreases mortality in severe and fulminant Clostridioides difficile infection in critically ill patients

Tixier, E., Verheyen, E., Ungaro, R., & Grinspan, A. (2019). Faecal microbiota transplant decreases mortality in severe and fulminant Clostridioides difficile infection in critically ill patients. Alimentary Pharmacology & Therapeutics. doi:10.1111/apt.15526

Frail Heart, Friable Colon: A Case Report of Fecal Microbiota Transplant for Refractory Clostridium difficile Infection in a Patient with Recent Trans-Catheter Aortic Valve Replacement

Bhanvadia, A. (2018) Frail Heart, Friable Colon: A Case Report of Fecal Microbiota Transplant for Refractory Clostridium difficile Infection in a Patient with Recent Trans-Catheter Aortic Valve Replacement. J Inflam Bowel Dis & Discord 3(1): 124.

Fecal microbiota transplantation for the treatment of recurrent and severe Clostridium difficile infection in solid organ transplant recipients: A multicenter experience

Cheng, Y. W., Phelps E., Ganapini V., Khan N., Ouyang, F., Xu H., … & Fischer M. (2018) Fecal microbiota transplantation for the treatment of recurrent and severe Clostridium difficile infection in solid organ transplant recipients: A multicenter experience. American Journal of Transplantation, 10.1111/ajt.15058.

Asymptomatic Clostridium difficile carriage rate post-fecal microbiota transplant is low: a prospective clinical and stool assessment.

Allegretti, J. R., Allegretti, A. S., Phelps, E., Xu, H., Kassam, Z., & Fischer, M. (2017). Asymptomatic Clostridium difficile carriage rate post-fecal microbiota transplant is low: a prospective clinical and stool assessment. Clinical Microbiology and Infection

The association of donor stool consistency by Bristol stool scale on microbial profile and clinical outcomes of fecal microbiota transplantation in Clostridium difficile infection

Budree, S., Rao, S., Allegretti, J. R., Fischer, M., Kelly, C. R., Smith, M., … & Kassam, Z. (2017). The Association of Donor Stool Consistency by Bristol Stool Scale on Microbial Profile and Clinical Outcomes of Fecal Microbiota Transplantation in Clostridium Difficile Infection. Gastroenterology, 152(5), S630.

Fecal microbiota transplantation is safe and effective for the treatment of Clostridium difficile infection in solid organ transplant recipients

Piceno, Y. M., El-Nachef, N., Kassam, Z., Smith, M., Lynch, K., Zydek, M., … & Lynch, S. (2017). Fecal Microbiota Transplantation Differentially Influences the Gut Microbiota of Clostridium Difficile Infection and Ileal Pouch Anal Anastomosis Patients. Gastroenterology, 152(5), S1006.

Review of the Emerging Treatment of Clostridium difficile Infection with Fecal Microbiota Transplantation and Insights into Future Challenges

Kassam, Z., Lee, C., & Hunt, R. (2014). Review of the Emerging Treatment of Clostridium difficile Infection with Fecal Microbiota Transplantation and Insights into Future Challenges. Clinics In Laboratory Medicine, 34(4), 787-798. doi:10.1016/j.cll.2014.08.007

Pilot study of autologous fecal microbiota transplants in nursing home residents: Feasibility and safety

Liu CK, Seo J, Pravodelov V, Frazier S, Guy M, Concilio K, Lau-Ng R, Brandeis G, Watson J, van der Velde J, Olesen SW, Budree S, Njenga M, Kassam Z, Osman M. Pilot study of autologous fecal microbiota transplants in nursing home residents: Feasibility and safety. Contemp Clin Trials Commun. 2022 Mar 7;27:100906. doi: 10.1016/j.conctc.2022.100906. PMID: 35299780; PMCID: PMC8921299

Stool Banking for Fecal Microbiota Transplantation: Methods and Operations at a Large Stool Bank

Chen, J., Zaman, A., Ramakrishna, B., & Olesen, S. (2021). Stool Banking for Fecal Microbiota Transplantation: Methods and Operations at a Large Stool Bank. Frontiers In Cellular And Infection Microbiology, 11. doi: 10.3389/fcimb.2021.622949

Oral Fecal Microbiota Transplant Capsules Are Safe and Effective for Recurrent Clostridioides difficile Infection

Du, C., Luo, Y., Walsh, S., & Grinspan, A. (2021). Oral Fecal Microbiota Transplant Capsules Are Safe and Effective for Recurrent Clostridioides difficile Infection. Journal Of Clinical Gastroenterology, 55(4), 300-308. doi: 10.1097/mcg.0000000000001495

Updates and Challenges in Fecal Microbiota Transplantation for Clostridioides difficile Infection in Children

Hourigan, S., Nicholson, M., Kahn, S., & Kellermayer, R. (2021). Updates and Challenges in Fecal Microbiota Transplantation for Clostridioides difficile Infection in Children. Journal Of Pediatric Gastroenterology & Nutrition, Publish Ahead of Print. doi: 10.1097/mpg.0000000000003229

Fecal Microbiota Transplantation Is Highly Effective in Real-World Practice: Initial Results From the FMT National Registry

Kelly, C., Yen, E., Grinspan, A., Kahn, S., Atreja, A., & Lewis, J. et al. (2021). Fecal Microbiota Transplantation Is Highly Effective in Real-World Practice: Initial Results From the FMT National Registry. Gastroenterology, 160(1), 183-192.e3. doi: 10.1053/j.gastro.2020.09.038

Fecal Microbiota Transplantation for Recurrent C difficile Infection During the COVID-19 Pandemic

Khanna, S., Tande, A., Rubin, D., Khoruts, A., Kahn, S., & Pardi, D. (2021). Fecal Microbiota Transplantation for Recurrent C difficile Infection During the COVID-19 Pandemic. Mayo Clinic Proceedings, 96(6), 1418-1425. doi: 10.1016/j.mayocp.2021.04.005

Fecal Microbiota Transplantation Is Safe for Clostridiodies difficile Infection in Patients with Solid Tumors

Mendelsohn, R., Kaltsas, A., King, S., Hwang, C., Kassam, Z., & Abend, A. et al. (2021). Fecal Microbiota Transplantation Is Safe for Clostridiodies difficile Infection in Patients with Solid Tumors Undergoing Chemotherapy. Digestive Diseases And Sciences. doi: 10.1007/s10620-021-07024-z

Current Challenges in Fecal Microbiota Transplantation for Clostridioides difficile Infection in Children

Nicholson, M., Hourigan, S., Conrad, M., Goyal, A., Jensen, K., & Kelsen, J. et al. (2021). Current Challenges in Fecal Microbiota Transplantation for Clostridioides difficile Infection in Children. American Journal Of Gastroenterology, Publish Ahead of Print. doi: 10.14309/ajg.0000000000001350

Stool processing speed and storage duration do not impact the clinical effectiveness of fecal microbiota transplantation

Jessica R. Allegretti, Ryan J. Elliott, Alim Ladha, Mary Njenga, Kurt Warren, Kelsey O’Brien, Shrish Budree, Majdi Osman, Monika Fischer, Colleen R. Kelly & Zain Kassam (2020): Stool processing speed and storage duration do not impact the clinical effectiveness of fecal microbiota transplantation. Gut Microbes, DOI: 10.1080/19490976.2020.1768777

Long-Term Outcomes Following Multiply Recurrent Clostridioides Difficile Infection and Fecal Microbiota Transplantation

Dawwas G, Brensinger CM, Vajravelu RK, Wu Q, Kelly CR, Laine L, Wu GD, Lewis JD. Long-Term Outcomes Following Multiply Recurrent Clostridioides Difficile Infection and Fecal Microbiota Transplantation. Clin Gastroenterol Hepatol. 2020 Dec 8:S1542-3565(20)31642-6. doi: 10.1016/j.cgh.2020.12.004. Epub ahead of print. PMID: 33307184

Monitoring Fecal Microbiota Transplantation Practice in a Rapidly Evolving Health and Regulatory Environment

Kelly, C., Laine, L., & Wu, G. (2020). Monitoring Fecal Microbiota Transplantation Practice in a Rapidly Evolving Health and Regulatory Environment. Gastroenterology, 159(6), 2004-2006. doi: 10.1053/j.gastro.2020.08.039

Systematic review: the global incidence of faecal microbiota transplantation-related adverse events from 2000 to 2020

Marcella C, Cui B, Kelly CR, Ianiro G, Cammarota G, Zhang F. Systematic review: the global incidence of faecal microbiota transplantation-related adverse events from 2000 to 2020. Aliment Pharmacol Ther. 2020 Nov 7. doi: 10.1111/apt.16148. Epub ahead of print. PMID: 33159374.

Ulcerative Proctitis in a Patient With a History of Fecal Microbiota Transplant for Clostridioides difficile Infection

Massaro, M., Vansia, J., & McGill, S. (2020). Ulcerative Proctitis in a Patient With a History of Fecal Microbiota Transplant for Clostridioides difficile Infection. ACG Case Reports Journal, 7(4), e00364. doi: 10.14309/crj.0000000000000364

Risk Factors that Predict the Failure of Multiple Fecal Microbiota Transplantations for Clostridioides difficile Infection

Allegretti, J., Mehta, S., Kassam, Z., Kelly, C., Kao, D., Xu, H., & Fischer, M. (2020). Risk Factors that Predict the Failure of Multiple Fecal Microbiota Transplantations for Clostridioides difficile Infection. Digestive Diseases And Sciences. doi:10.1007/s10620-020-06198-2

The evolution of the use of faecal microbiota transplantation and emerging therapeutic indications

Allegretti, J., Mullish, B., Kelly, C., & Fischer, M. (2019). The evolution of the use of faecal microbiota transplantation and emerging therapeutic indications. The Lancet, 394(10196), 420-431. doi:10.1016/s0140-6736(19)31266-8

Risk of Clostridium difficile Infection with Systemic Antimicrobial Therapy Following Successful Fecal Microbiota Transplant: Should We Recommend Anti-Clostridium difficile Antibiotic Prophylaxis?

Allegretti, J., Kao, D., Phelps, E., Roach, B., Smith, J., & Ganapini, V. et al. (2019). Risk of Clostridium difficile Infection with Systemic Antimicrobial Therapy Following Successful Fecal Microbiota Transplant: Should We Recommend Anti-Clostridium difficile Antibiotic Prophylaxis?. Digestive Diseases And Sciences. doi:10.1007/s10620-018-5450-4

Risk Factors for Gastrointestinal Symptoms Following Successful Eradication of Clostridium difficile by Fecal Microbiota Transplantation (FMT)

Allegretti, J.R., Kassam, Z., Fischer, M., Kelly, C., & Chan W.W. (2019). Risk Factors for Gastrointestinal Symptoms Following Successful Eradication of Clostridium difficile by Fecal Microbiota Transplantation (FMT). Journal Of Clinical Gastroenterology, 1. doi:10.1097/mcg.0000000000001194

Where Stool is a Drug: International Approaches to Regulating the use of Fecal Microbiota for Transplantation

Scheeler A. Where Stool is a Drug: International Approaches to Regulating the use of Fecal Microbiota for Transplantation. J Law Med Ethics. 2019 Dec;47(4):524-540. doi: 10.1177/1073110519897729. PMID: 31957572.

Outcomes of a Multidisciplinary Clinic in Evaluating Recurrent Clostridioides difficile Infection Patients for Fecal Microbiota Transplant: A Retrospective Cohort Analysis

Shin, J., Chaplin, A., Hays, R., Kolling, G., Vance, S., & Guerrant, R. et al. (2019). Outcomes of a Multidisciplinary Clinic in Evaluating Recurrent Clostridioides difficile Infection Patients for Fecal Microbiota Transplant: A Retrospective Cohort Analysis. Journal Of Clinical Medicine, 8(7), 1036. doi:10.3390/jcm8071036

Small Intestinal Bacterial Overgrowth: Should Screening Be Included in the Pre-fecal Microbiota Transplantation Evaluation?

Allegretti, J. R., Kassam, Z., & Chan, W. W. (2018). Small Intestinal Bacterial Overgrowth: Should Screening Be Included in the Pre-fecal Microbiota Transplantation Evaluation?. Digestive diseases and sciences, 63(1), 193-197.

The 5D framework: a clinical primer for fecal microbiota transplantation to treat Clostridium difficile infection

Allegretti, J. R., Kassam, Z., Osman, M., Budree, S., Fischer, M., & Kelly, C. R. (2018). The 5D framework: a clinical primer for fecal microbiota transplantation to treat Clostridium difficile infection. Gastrointestinal endoscopy, 87(1), 18-29.

Changes in microbiota composition, bile and fatty acid metabolism, in successful faecal microbiota transplantation for Clostridioides difficile infection

Brown, J. R. M., Flemer, B., Joyce, S. A., Zulquernain, A., Sheehan, D., Shanahan, F., & O’Toole, P. W. (2018). Changes in microbiota composition, bile and fatty acid metabolism, in successful faecal microbiota transplantation for Clostridioides difficile infection. BMC Gastroenterology, 18(1), 131.

Do Clinical Factors Affect Microbial Engraftment After Fecal Microbiota Transplantation in Recurrent Clostridium difficile Infection?

Budree, S., Osman, M., Panchal, P., Shu, E., Carrellas, M., Kassam, Z., & Allegretti, J. (2018, November). 618. Do Clinical Factors Affect Microbial Engraftment After Fecal Microbiota Transplantation in Recurrent Clostridium difficile Infection?. Open Forum Infectious Diseases (Vol. 5, No. suppl_1, pp. S225-S226). US: Oxford University Press.

Early Results of Fecal Microbial Transplantation Protocol Implementation at a Community-based University Hospital

Duarte-Chavez, R., Wojda, T. R., Zanders, T. B., Geme, B., Fioravanti, G., & Stawicki, S. P. (2018). Early results of fecal microbial transplantation protocol implementation at a community-based university hospital. Journal of global infectious diseases, 10(2), 47.

Scaling Access to Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection in the United States: A Geospatial Time-Series Analysis from 2013 to 2017

Panchal, P., Elliott, R. J., Budree, S., Osman, M., Allegretti, J. R., Kelly, C. R., … & Kassam, Z. (2018). 1010-Scaling Access to Fecal Microbiota Transplantation for Recurrent Clostridium Difficle Infection in the United States: A Geospatial Time-Series Analysis from 2013 to 2017. Gastroenterology, 154(6), S-190.

Scaling Pediatric Access to Fecal Microbiota Transplantation in the United States: A Time-Series Geospatial Analysis

Panchal, P., Kahn, S., Zellmer, C., Kassam, Z., Osman, M., Allegretti, J., … & NASPGHAN FMT Special Interest Group. (2018, November). 533. Scaling Pediatric Access to Fecal Microbiota Transplantation in the United States: A Time-Series Geospatial Analysis. Open Forum Infectious Diseases (Vol. 5, No. suppl_1, pp. S197-S197). US: Oxford University Press.

Strain Tracking Reveals the Determinants of Bacterial Engraftment in the Human Gut Following Fecal Microbiota Transplantation

Smillie, C. S., Sauk, J., Gevers, D., Friedman, J., Sung, J., Youngster, I., … & Allegretti, J. R. (2018). Strain tracking reveals the determinants of bacterial engraftment in the human gut following fecal microbiota transplantation. Cell host & microbe, 23(2), 229-240.

Early Antibiotic Use After Fecal Microbiota Transplantation Increases Risk of Treatment Failure

Allegretti, J. R., Kao, D., Sitko, J., Fischer, M., & Kassam, Z. (2017). Early Antibiotic Use After Fecal Microbiota Transplantation Increases Risk of Treatment Failure. Clinical Infectious Diseases, 66(1), 134-135.

Classifying Fecal Microbiota Transplantation Failure: An Observational Study Examining Timing and Characteristics of Fecal Microbiota Transplantation Failures.

Allegretti, J. R., Phelps, E., Allegretti, A., Xu, H., Fischer, M., & Kassam, Z. (2017). Classifying Fecal Microbiota Transplantation Failure: An Observational Study Examining Timing and Characteristics of Fecal Microbiota Transplantation Failures. Clinical gastroenterology and hepatology: the official clinical practice journal of the American Gastroenterological Association.

Should we recommend anti-Clostridium difficile antibiotic or probiotic prophylaxis? Risk of Clostridium difficile infection with systemic antimicrobial therapy following successful fecal microbiota transplant

Fischer, M., Kao, D. H., Phelps, E. L., Smith, J. D., Roach, B., Kassam, Z., … & Allegretti, J. R. (2017). Should we Recommend Anti-Clostridium Difficile Antibiotic or Probiotic Prophylaxis?: Risk of Clostridium Difficile Infection with Systemic Antimicrobial Therapy Following Successful Fecal Microbiota Transplant. Gastroenterology, 152(5), S1005.

Fecal microbiota transplantation is safe and effective for the treatment of Clostridium difficile infection in solid organ transplant recipients

Fischer, M., Khan, M., Phelps, E. L., Safdar, N., Misch, E. A., Kaur, N., … & Xu, H. (2017). Fecal Microbiota Transplantation is Safe and Effective for the Treatment of Clostridium Difficile Infection in Solid Organ Transplant Recipients. Gastroenterology, 152(5), S1005.

Fecal microbiota transplant in severe and severe complicated Clostridium difficile: a promising treatment approach

Fischer, M., Sipe, B., Cheng, Y. W., Phelps, E., Rogers, N., Sagi, S., … & Kassam, Z. (2017). Fecal microbiota transplant in severe and severe-complicated Clostridium difficile: A promising treatment approach. Gut microbes, 8(3), 289-302.

Prevalence of early antibiotic use post-fecal microbiota transplantation and corresponding risk of FMT failure.

Allegretti, J. R., Kao, D. H., Sitko, J., Fischer, M., & Kassam, Z. (2017). Prevalence of Early Antibiotic Use Post-Fecal Microbiotatransplantation and Corresponding Risk of FMT Failure. Gastroenterology, 152(5), S342-S343.

Pediatric access to fecal microbiota transplantation for recurrent Clostridium difficile Infection in the United States and the impact of stool banks: a geospatial analysis

Panchal, P., Budree, S., Tu, E., Kahn, S. A., Allegretti, J. R., Fischer, M., … & Osman, M. (2017). Pediatric Access to Fecal Microbiota Transplantation for Recurrent Clostridium Difficile Infection in the United States and the Impact of Stool Banks: A Geospatial Analysis. Gastroenterology, 152(5), S849-S850.

Faecal microbiota transplantation for Clostridium difficile infection: a multicentre study of non-responders

Razik, R., Osman, M., Lieberman, A., Allegretti, J. R., & Kassam, Z. (2017). Faecal microbiota transplantation for Clostridium difficile infection: a multicentre study of non-responders. N Engl J Med, 368, 407-415.

Limited engraftment of donor microbiome via one-time fecal microbial transplantation in treated HIV-infected individuals

Vujkovic-Cvijin, I., Rutishauser, R. L., Pao, M., Hunt, P. W., Lynch, S. V., McCune, J. M., & Somsouk, M. (2017). Limited engraftment of donor microbiome via one-time fecal microbial transplantation in treated HIV-infected individuals. Gut microbes, 8(5), 440-450.

Safety and Efficacy of Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection From An International Public Stool Bank: Results From a 2050-Patient Multicenter Cohort

Osman, M., O’Brien, K., Stoltzner, Z., Ling, K., Koelsch, E., & Dubois, N. et al. (2016). Safety and Efficacy of Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection From An International Public Stool Bank: Results From a 2050-Patient Multicenter Cohort. Open Forum Infectious Diseases, 3(suppl_1). doi:10.1093/ofid/ofw172.1668

Prospective Assessment of Donor Eligibility for Fecal Microbiota Transplantation at a Public Stool Bank: Results From the Evaluation of 1,387 Candidate Donors

Dubois, N., Ling, K., Osman, M., Burns, L., Mendolia, G., Blackler, D., Burgess, J., Edelstein, C., Noh, A., Vo, E., Alm E., Smith, M., and Kassam, Z. (2015). Prospective Assessment of Donor Eligibility for Fecal Microbiota Transplantation at a Public Stool Bank: Results From the Evaluation of 1,387 Candidate Donors. Idsa. Retrieved from https://idsa.confex.com/idsa/2015/webprogram/Paper52979.html

Challenges of Screening Prospective Stool Donors for Fecal Microbiota Transplantation

Dubois, N., Read, C., O’Brien, K., and Ling, K. (2020). Biological Research For Nursing. Challenges of Screening Prospective Stool Donors for Fecal Microbiota Transplantation. Retrieved from https://journals.sagepub.com/doi/abs/10.1177/1099800420941185

Competitively Selected Donor Fecal Microbiota Transplantation: Butyrate Concentration and Diversity as Measures of Donor Quality

Barnes, D., Ng, K., Smits, S., Sonnenburg, J., Kassam, Z., & Park, K. T. (2018). Competitively Selected Donor Fecal Microbiota Transplantation: Butyrate Concentration and Diversity as Measures of Donor Quality. Journal of pediatric gastroenterology and nutrition.

Does the Donor Matter? Microbiome Sequencing to Evaluate Lower Donor Efficacy in Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection

Osman, M., Abend, A., Panchal, P., Kassam, Z., & Budree, S. (2018). 88-Does the Donor Matter? Microbiome Sequencing to Evaluate Lower Donor Efficacy in Fecal Microbiota Transplantation for Recurrent Clostridium Difficile Infection. Gastroenterology, 154(6), S-25.

Donor stool processing time: the effect on the intestinal microbiome and clinical outcomes of fecal microbiota transplantation in Clostridium difficile Infection

Budree, S., Elliott, R. J., Rao, S., Njenga, M., Ladha, A., Allegretti, J. R., … & Kassam, Z. (2017). Donor Stool Processing Time: The Effect on the Intestinal Microbiome and Clinical Outcomes of Fecal Microbiota Transplantation in Clostridium Difficile Infection. Gastroenterology, 152(5), S1006.

The association of donor stool consistency by Bristol stool scale on microbial profile and clinical outcomes of fecal microbiota transplantation in Clostridium difficile infection

Budree, S., Rao, S., Allegretti, J. R., Fischer, M., Kelly, C. R., Smith, M., … & Kassam, Z. (2017). The Association of Donor Stool Consistency by Bristol Stool Scale on Microbial Profile and Clinical Outcomes of Fecal Microbiota Transplantation in Clostridium Difficile Infection. Gastroenterology, 152(5), S630.

The association of stool donor diet on microbial profile and clinical outcomes of fecal microbiota transplantation in clostridium difficile infection

Budree, S., Tu, E., Leith, T., Allegretti, J. R., Rao, S., Day, R., … & Osman, M. (2017). The Association of Stool Donor Diet on Microbial Profile and Clinical Outcomes of Fecal Microbiota Transplantation in Clostridium Difficile Infection. Gastroenterology, 152(5), S630-S631.

Do Specific Bacteria Drive Clinical Cure in Fecal Microbiota Transplantation for Clostridium Difficile Infection?: Clinical, Microbial and Metabolomic Characterization of Universal FMT Donors

Budree, S., Wong, W. F., Tu, E., Rao, S., Allegretti, J. R., Fischer, M., … & Kassam, Z. (2017). Do Specific Bacteria Drive Clinical Cure in Fecal Microbiota Transplantation for Clostridium Difficile Infection?: Clinical, Microbial and Metabolomic Characterization of Universal FMT Donors. Gastroenterology, 152(5), S349.

Stool Donor Body Mass Index Does Not Affect Recipient Weight After a Single Fecal Microbiota Transplantation for Clostridium difficile Infection

Fischer, M., Kao, D., Kassam, Z., Smith, J., Louie, T., Sipe, B., … & Allegretti, J. R. (2017). Stool Donor Body Mass Index Does Not Affect Recipient Weight After a Single Fecal Microbiota Transplantation for C. difficile Infection. Clinical gastroenterology and hepatology: the official clinical practice journal of the American Gastroenterological Association.

Dynamic Colonization of Microbes and Their Functions after Fecal Microbiota Transplantation for Inflammatory Bowel Disease

Chu ND, Crothers JW, Nguyen LTT, Kearney SM, Smith MB, Kassam Z, Collins C, Xavier R, Moses PL, Alm EJ. Dynamic Colonization of Microbes and Their Functions after Fecal Microbiota Transplantation for Inflammatory Bowel Disease. mBio. 2021 Aug 31;12(4):e0097521. doi: 10.1128/mBio.00975-21. Epub 2021 Jul 20. PMID: 34281401; PMCID: PMC8406238.

Effect of antibiotic pretreatment on bacterial engraftment after Fecal Microbiota Transplant (FMT) in IBS-D

Singh P, Alm EJ, Kelley JM, Cheng V, Smith M, Kassam Z, Nee J, Iturrino J, Lembo A. Effect of antibiotic pretreatment on bacterial engraftment after Fecal Microbiota Transplant (FMT) in IBS-D. Gut Microbes. 2022 Jan-Dec;14(1):2020067. doi: 10.1080/19490976.2021.2020067. PMID: 35014601; PMCID: PMC8757476.

Fecal Microbiota Transplantation for the Treatment of Ulcerative Colitis: A Qualitative Assessment of Patient Perceptions and Experiences

Chauhan U, Popov J, Farbod Y, Kalantar M, Wolfe M, Moayyedi P, Marshall JK, Halder S, Kaasalainen S. Fecal Microbiota Transplantation for the Treatment of Ulcerative Colitis: A Qualitative Assessment of Patient Perceptions and Experiences. J Can Assoc Gastroenterol. 2021 Mar 26;4(6):e120-e129. doi: 10.1093/jcag/gwab007. PMID: 34877470; PMCID: PMC8643654.

Daily, oral FMT for long-term maintenance therapy in ulcerative colitis: results of a single-center, prospective, randomized pilot study

Crothers JW, Chu ND, Nguyen LTT, Phillips M, Collins C, Fortner K, Del Rio-Guerra R, Lavoie B, Callas P, Velez M, Cohn A, Elliott RJ, Wong WF, Vo E, Wilcox R, Smith M, Kassam Z, Budd R, Alm EJ, Mawe GM, Moses PL. Daily, oral FMT for long-term maintenance therapy in ulcerative colitis: results of a single-center, prospective, randomized pilot study. BMC Gastroenterol. 2021 Jul 8;21(1):281. doi: 10.1186/s12876-021-01856-9. PMID: 34238227; PMCID: PMC8268596.

Diagnosis and management of Clostridioides difficile infection in patients with inflammatory bowel disease

Dalal RS, Allegretti JR. Diagnosis and management of Clostridioides difficile infection in patients with inflammatory bowel disease. Curr Opin Gastroenterol. 2021 Mar 3. doi: 10.1097/MOG.0000000000000739. Epub ahead of print. PMID: 33654015.

Fecal Microbiota Transplantation for Chronic Pouchitis: Promising Novel Therapeutic or Lost Cause?

Dalal RS, Allegretti JR. Fecal Microbiota Transplantation for Chronic Pouchitis: Promising Novel Therapeutic or Lost Cause? Inflamm Bowel Dis. 2021 Jan 27:izab002. doi: 10.1093/ibd/izab002. Epub ahead of print. PMID: 33501941.

Transferable IgA-coated Odoribacter splanchnicus in Responders to Fecal Microbiota Transplantation for Ulcerative Colitis Limits Colonic Inflammation

Lima S, Gogokhia L, Viladomiu M, Chou L, Putzel G, Jin W, Pires S, Guo CJ, Gerardin Y, Crawford CV, Jacob V, Scherl E, Brown SE, Hambor J, Longman R. Transferable IgA-coated Odoribacter splanchnicus in Responders to Fecal Microbiota Transplantation for Ulcerative Colitis Limits Colonic Inflammation. Gastroenterology. 2021 Oct 1:S0016-5085(21)03610-6. doi: 10.1053/j.gastro.2021.09.061. Epub ahead of print. PMID: 34606847.

Inflammatory Bowel Disease Outcomes Following Fecal Microbiota Transplantation for Recurrent C. difficile Infection

Allegretti JR, Kelly CR, Grinspan A, Mullish BH, Hurtado J, Carrellas M, Marcus J, Marchesi JR, McDonald JAK, Gerardin Y, Silverstein M, Pechlivanis A, Barker GF, Miguens Blanco J, Alexander JL, Gallagher KI, Pettee W, Phelps E, Nemes S, Sagi SV, Bohm M, Kassam Z, Fischer M. Inflammatory Bowel Disease Outcomes Following Fecal Microbiota Transplantation for Recurrent C. difficile Infection. Inflamm Bowel Dis. 2020 Nov 6:izaa283. doi: 10.1093/ibd/izaa283. Epub ahead of print. PMID: 33155639.

Fecal transplantation for ulcerative colitis: current evidence and future applications

Loris R. Lopetuso, Gianluca Ianiro, Jessica R. Allegretti, Stefano Bibbò, Antonio Gasbarrini, Franco Scaldaferri & Giovanni Cammarota (2020) Fecal transplantation for ulcerative colitis: current evidence and future applications. Expert Opinion on Biological Therapy, 20(3). DOI: 10.1080/14712598.2020.1733964

Re-Evaluating the Evidence for Faecal Microbiota Transplantation ‘Super-Donors’ in Inflammatory Bowel Disease

Olesen, S., & Gerardin, Y. (2020). Re-Evaluating the Evidence for Faecal Microbiota Transplantation ‘Super-Donors’ in Inflammatory Bowel Disease. Journal Of Crohn’s And Colitis, 15(3), 453-461. doi: 10.1093/ecco-jcc/jjaa170

Expansion of Bacteriophages Is Linked to Aggravated Intestinal Inflammation and Colitis.

Gogokhia, L., Buhrke, K., Bell, R., Hoffman, B., Brown, D., & Hanke-Gogokhia, C. et al. (2019). Expansion of Bacteriophages Is Linked to Aggravated Intestinal Inflammation and Colitis. Cell Host & Microbe, 25(2), 285-299.e8. doi:10.1016/j.chom.2019.01.008

Fecal microbiota transplant for Crohn disease: A study evaluating safety, efficacy, and microbiome profile

Gutin, L., Piceno, Y., Fadrosh, D., Lynch, K., Zydek, M., & Kassam, Z. et al. (2019). Fecal microbiota transplant for Crohn disease: A study evaluating safety, efficacy, and microbiome profile. United European Gastroenterology Journal, 7(6), 807-814. doi:10.1177/2050640619845986

Combined Endoscopic and Oral Fecal Microbiota Transplantation in Patients with Antibiotic-Dependent Pouchitis: Low Clinical Efficacy due to Low Donor Microbial Engraftment

Herfarth, H., Barnes, E. L., Long, M. D., Isaacs, K. L., Leith, T., Silverstein, M., … Kassam, Z. (2019). Combined Endoscopic and Oral Fecal Microbiota Transplantation in Patients with Antibiotic-Dependent Pouchitis: Low Clinical Efficacy due to Low Donor Microbial Engraftment. Inflammatory Intestinal Diseases, 1–6. doi:10.1159/000497042

Fecal Microbiota Transplantation in Pouchitis: Clinical, Endoscopic, Histologic, and Microbiota Results from a Pilot Study

Selvig, D., Piceno, Y., Terdiman, J., Zydek, M., Umetsu, S., & Balitzer, D. et al. (2019). Fecal Microbiota Transplantation in Pouchitis: Clinical, Endoscopic, Histologic, and Microbiota Results from a Pilot Study. Digestive Diseases And Sciences. doi:10.1007/s10620-019-05715-2

The Current Landscape and Lessons from Fecal Microbiota Transplantation for Inflammatory Bowel Disease: Past, Present and Future

Allegretti, J., Eysenbach, L. M., El-Nachef, N., Fischer, M., Kelly, C., & Kassam, Z. (2017). The Current Landscape and Lessons from Fecal Microbiota Transplantation for Inflammatory Bowel Disease: Past, Present, and Future. Inflammatory bowel diseases, 23(10), 1710-1717.

Differences in Clinical Course, Genetics, and the Microbiome Between Familial and Sporadic Inflammatory Bowel Diseases

Borren, N. Z., Conway, G., Garber, J. J., Khalili, H., Budree, S., Mallick, H., … & Ananthakrishnan, A. N. (2017). Differences in Clinical Course, Genetics, and the Microbiome Between Familial and Sporadic Inflammatory Bowel Diseases. Journal of Crohn’s and Colitis, 12(5), 525-531.

Does Rifaximin prior to fecal microbiota transplantation improve clinical outcomes compared to microbiome restoration alone in ulcerative colitis? A cohort study evaluating the impact of non-absorbable antibiotic pretreatment

El-Nachef, N., Kassam, Z., Piceno, Y. M., Ablaza, A. J., Zydek, M., Elliott, R. J., … & Somsouk, M. (2017). Does Rifaximin Prior to Fecal Microbiota Transplantation Improve Clinical Outcomes Compared to Microbiome Restoration Alone in Ulcerative Colitis? a Cohort Study Evaluating the Impact of Non-Absorbable Antibiotic Pretreatment. Gastroenterology, 152(5), S1008-S1009.

The role of fecal microbiota transplantation in ulcerative colitis and Crohn’s disease: results from a parallel inflammatory bowel disease cohort study

El-Nachef, N., Piceno, Y. M., Kassam, Z., Ablaza, A. J., Zydek, M., Lynch, K., … & Lynch, S. (2017). The Role of Fecal Microbiota Transplantation in Ulcerative Colitis and Crohn’s Disease: Results from a Parallel Inflammatory Bowel Disease Cohort Study. Gastroenterology, 152(5), S1008.

Can you cause inflammatory bowel disease with fecal transplantation? A 31-patient case-series of fecal transplantation using stool from a donor who later developed Crohn’s disease

Fischer, M., Bittar, M., Papa, E., Kassam, Z., & Smith, M. (2017). Can you cause inflammatory bowel disease with fecal transplantation? A 31-patient case-series of fecal transplantation using stool from a donor who later developed Crohn’s disease. Gut microbes, 8(3), 205-207.

Single Delivery of High-Diversity Fecal Microbiota Preparation by Colonoscopy Is Safe and Effective in Increasing Microbial Diversity in Active Ulcerative Colitis

Jacob, V., Crawford, C., Cohen-Mekelburg, S., Viladomiu, M., Putzel, G. G., Schneider, Y., … & Ajami, N. J. (2017). Single delivery of high-diversity fecal microbiota preparation by colonoscopy is safe and effective in increasing microbial diversity in active ulcerative colitis. Inflammatory bowel diseases, 23(6), 903-911.

A Surgical Clostridium-associated Risk of Death Score Predicts Mortality after Colectomy for Clostridium difficile

Kulaylat, A. S., Kassam, Z., Hollenbeak, C. S., & Stewart Sr, D. B. (2017). A Surgical Clostridium-Associated Risk of Death Score Predicts Mortality After Colectomy for Clostridium difficile. Diseases of the Colon & Rectum, 60(12), 1285-1290.

Systematic Review and Meta-Analysis: Fecal Microbiota Transplantation for Treatment of Active Ulcerative Colitis

Narula, N., Kassam, Z., Yuan, Y., Colombel, J. F., Ponsioen, C., Reinisch, W., & Moayyedi, P. (2017). Systematic review and meta-analysis: Fecal microbiota transplantation for treatment of active ulcerative colitis. Inflammatory bowel diseases, 23(10), 1702-1709.

Fecal microbiota transplantation differentially influences the gut microbiota of Clostridium difficile infection and ileal pouch anal anastomosis patients

Piceno, Y. M., El-Nachef, N., Kassam, Z., Smith, M., Lynch, K., Zydek, M., … & Lynch, S. (2017). Fecal Microbiota Transplantation Differentially Influences the Gut Microbiota of Clostridium Difficile Infection and Ileal Pouch Anal Anastomosis Patients. Gastroenterology, 152(5), S1006.

The Risk of Inflammatory Bowel Disease Flares after Fecal Microbiota Transplantation: Systematic Review and Meta-Analysis

Qazi, T., Amaratunga, T., Barnes, E. L., Fischer, M., Kassam, Z., & Allegretti, J. R. (2017). The risk of inflammatory bowel disease flares after fecal microbiota transplantation: Systematic review and meta-analysis. Gut microbes, 8(6), 574-588.

Fecal Microbiota Transplantation is Safe and Efficacious for Recurrent or Refractory Clostridium difficile Infection in Patients with Inflammatory Bowel Disease

Fischer, M., Kao, D., Kelly, C., Kuchipudi, A., Jafri, S. M., Blumenkehl, M., … & Cook, G. (2016). Fecal microbiota transplantation is safe and efficacious for recurrent or refractory Clostridium difficile infection in patients with inflammatory bowel disease. Inflammatory bowel diseases, 22(10), 2402-2409.

Chronic Liver Diseases and the Microbiome: Translating Our Knowledge of Gut Microbiota to Management of Chronic Liver Disease

Acharya C, Bajaj JS. Chronic Liver Diseases and the Microbiome: Translating Our Knowledge of Gut Microbiota to Management of Chronic Liver Disease. Gastroenterology. 2020 Nov 27:S0016-5085(20)35504-9. doi: 10.1053/j.gastro.2020.10.056. Epub ahead of print. PMID: 33253686.

Microbiota changes and intestinal microbiota transplantation in liver diseases and cirrhosis

Bajaj JS, Khoruts A. Microbiota changes and intestinal microbiota transplantation in liver diseases and cirrhosis. J Hepatol. 2020 May;72(5):1003-1027. doi: 10.1016/j.jhep.2020.01.017. Epub 2020 Jan 28. PMID: 32004593.

Fecal Microbiota Transplant in Cirrhosis Reduces Gut Microbial Antibiotic Resistance Genes: Analysis of Two Trials

Bajaj JS, Shamsaddini A, Fagan A, Sterling RK, Gavis E, Khoruts A, Fuchs M, Lee H, Sikaroodi M, Gillevet PM. Fecal Microbiota Transplant in Cirrhosis Reduces Gut Microbial Antibiotic Resistance Genes: Analysis of Two Trials. Hepatol Commun. 2020 Nov 21;5(2):258-271. doi: 10.1002/hep4.1639. PMID: 33553973; PMCID: PMC7850310.

Fecal Microbiota Transplantation is Safe and Effective in Patients with Clostridioides difficile Infection and Cirrhosis

Cheng YW, Alhaffar D, Saha S, et al. Fecal Microbiota Transplantation is Safe and Effective in Patients with Clostridioides difficile Infection and Cirrhosis [published online ahead of print, 2020 Jul 6]. Clin Gastroenterol Hepatol. 2020;S1542-3565(20)30915-0. doi:10.1016/j.cgh.2020.06.051

Fecal Microbiota Transplantation in Patients With Primary Sclerosing Cholangitis: A Pilot Clinical Trial

Allegretti, J., Kassam, Z., Carrellas, M., Mullish, B., Marchesi, J., & Pechlivanis, A. et al. (2019). Fecal Microbiota Transplantation in Patients With Primary Sclerosing Cholangitis. The American Journal Of Gastroenterology, 1. doi:10.14309/ajg.0000000000000115

Fecal Microbial Transplant Capsules Are Safe in Hepatic Encephalopathy: A Phase 1, Randomized, Placebo‐Controlled Trial

Bajaj, J., Salzman, N., Acharya, C., Sterling, R., White, M., & Gavis, E. et al. (2019). Fecal Microbial Transplant Capsules Are Safe in Hepatic Encephalopathy: A Phase 1, Randomized, Placebo‐Controlled Trial. Hepatology, 70(5), 1690-1703. doi:10.1002/hep.30690

Antibiotic-Associated Disruption of Microbiota Composition and Function in Cirrhosis Is Restored by Fecal Transplant

Bajaj, J. S., Kakiyama, G., Savage, T., Takei, H, Kassam, Z. A., Fagan, A., … & Gillevet, P. M. (2018). Antibiotic‐Associated Disruption of Microbiota Composition and Function in Cirrhosis Is Restored by Fecal Transplant. Hepatology, 68: 1549-1558.

Fecal microbiota transplant from a rational stool donor improves hepatic encephalopathy: A randomized clinical trial

Bajaj, J. S., Kassam, Z., Fagan, A., Gavis, E. A., Liu, E., Cox, I. J., … & Williams, R. (2017). Fecal microbiota transplant from a rational stool donor improves hepatic encephalopathy: A randomized clinical trial. Hepatology.

Fecal microbiota transplant using a precision medicine approach is safe, associated with lower hospitalization risk and improved cognitive function in recurrent hepatic encephalopathy

Bajaj, J. S., Kassam, Z., Fagan, A., Gavis, E., Liu, E. J., Kheradman, R., … & Alm, E. (2017). Fecal microbiota transplant using a precision medicine approach is safe, Associated with lower hospitalization risk and improved cognitive function in recurrent hepatic encephalopathy. Gastroenterology, 152(5), S906.

The Gut Microbiome in Autoimmune Hepatitis Links to Disease Progression and is Significantly Different from Lupus and Healthy Controls

Kumar, V., Vieira, S. M., Ruff, W., Dehner, C., Kassam, Z., Boyer, J. L., … & Kriegel, M. (2017, October). The Gut Microbiome in Autoimmune Hepatitis Links to Disease Progression and is Significantly Different from Lupus and Healthy Controls. HEPATOLOGY (Vol. 66, pp. 189A-189A).

Impact of fecal microbiota transplantation with capsules on the prevention of metabolic syndrome among patients with obesity

Allegretti JR, Kassam Z, Hurtado J, Marchesi JR, Mullish BH, Chiang A, Thompson CC, Cummings BP. Impact of fecal microbiota transplantation with capsules on the prevention of metabolic syndrome among patients with obesity. Hormones (Athens). 2021 Jan 9. doi: 10.1007/s42000-020-00265-z. Epub ahead of print. PMID: 33420959.

Fecal microbiota transplantation improves metabolic syndrome parameters: systematic review with meta-analysis based on randomized clinical trials

Proença IM, Allegretti JR, Bernardo WM, de Moura DTH, Ponte Neto AM, Matsubayashi CO, Flor MM, Kotinda APST, de Moura EGH. Fecal microbiota transplantation improves metabolic syndrome parameters: systematic review with meta-analysis based on randomized clinical trials. Nutr Res. 2020 Nov;83:1-14. doi: 10.1016/j.nutres.2020.06.018. Epub 2020 Jul 3. PMID: 32987284.

Effects of Fecal Microbiota Transplantation With Oral Capsules in Obese Patients

Allegretti, J., Kassam, Z., Mullish, B., Chiang, A., Carrellas, M., & Hurtado, J. et al. (2019). Effects of Fecal Microbiota Transplantation With Oral Capsules in Obese Patients. Clinical Gastroenterology And Hepatology. doi:10.1016/j.cgh.2019.07.006

Does fecal microbiota transplantation from an obese donor lead to weight gain? A case series of 70 recipients

Fischer, M., Sipe, B., Torbeck, M., Xu, H., Kassam, Z., & Allegretti, J. R. (2017). Does fecal microbiota transplantation from an obese donor lead to weight gain? A case series of 70 recipients. Gastroenterology, 152(5), S1004.

Fecal Microbiota Transplantation (FMT) as an Adjunctive Therapy for Depression-Case Report

Beglinger C, Borgwardt S, Raes J, Schmidt A, Lang UE. Fecal Microbiota Transplantation (FMT) as an Adjunctive Therapy for Depression-Case Report. Front Psychiatry. 2022 Feb 17;13:815422. doi: 10.3389/fpsyt.2022.815422. PMID: 35250668; PMCID: PMC8891755.

Fecal Microbial Transplant in Individuals With Immune-Mediated Dry Eye

Watane A, Cavuoto KM, Rojas M, Dermer H, Day JO, Banerjee S, Galor A. Fecal Microbial Transplant in Individuals With Immune-Mediated Dry Eye. Am J Ophthalmol. 2022 Jan;233:90-100. doi: 10.1016/j.ajo.2021.06.022. Epub 2021 Jun 30. PMID: 34214453; PMCID: PMC8678170.

Precise quantification of bacterial strains after fecal microbiota transplantation delineates long-term engraftment and explains outcomes

Aggarwala V, Mogno I, Li Z, Yang C, Britton GJ, Chen-Liaw A, Mitcham J, Bongers G, Gevers D, Clemente JC, Colombel JF, Grinspan A, Faith J. Precise quantification of bacterial strains after fecal microbiota transplantation delineates long-term engraftment and explains outcomes. Nat Microbiol. 2021 Oct;6(10):1309-1318. doi: 10.1038/s41564-021-00966-0. Epub 2021 Sep 27. PMID: 34580445.

Progressive Shifts in the Gut Microbiome Reflect Prediabetes and Diabetes Development in a Treatment-Naive Mexican Cohort

Diener, C., Reyes-Escogido, M., Jimenez-Ceja, L., Matus, M., Gomez-Navarro, C., & Chu, N. et al. (2021). Progressive Shifts in the Gut Microbiome Reflect Prediabetes and Diabetes Development in a Treatment-Naive Mexican Cohort. Frontiers In Endocrinology, 11. doi: 10.3389/fendo.2020.602326

Functional Restoration of Bacteriomes and Viromes by Fecal Microbiota Transplantation

Fujimoto K, Kimura Y, Allegretti JR, Yamamoto M, Zhang YZ, Katayama K, Tremmel G, Kawaguchi Y, Shimohigoshi M, Hayashi T, Uematsu M, Yamaguchi K, Furukawa Y, Akiyama Y, Yamaguchi R, Crowe SE, Ernst PB, Miyano S, Kiyono H, Imoto S, Uematsu S. Functional Restoration of Bacteriomes and Viromes by Fecal Microbiota Transplantation. Gastroenterology. 2021 Feb 9:S0016-5085(21)00400-5. doi: 10.1053/j.gastro.2021.02.013. Epub ahead of print. PMID: 33577875.

SARS-CoV-2 vaccines and donor recruitment for FMT

Ianiro G, Mullish BH, Hvas CL, Segal JP, Kuijper EJ, Costello SP, Kelly CR, Allegretti JR, Fischer M, Iqbal TH, Satokari R, Kao D, van Prehn J, Ng SC, Bibbò S, Baunwall SMD, Quraishi MN, Sokol H, Zhang F, Keller J, Masucci L, Quaranta G, Kassam Z, Sanguinetti M, Tilg H, Gasbarrini A, Cammarota G. SARS-CoV-2 vaccines and donor recruitment for FMT. Lancet Gastroenterol Hepatol. 2021 Feb 8:S2468-1253(21)00032-7. doi: 10.1016/S2468-1253(21)00032-7. Epub ahead of print. PMID: 33571456.

Fecal microbiota transplantation in HIV: A pilot placebo-controlled study

Serrano-Villar S, Talavera-Rodríguez A, Gosalbes MJ, Madrid N, Pérez-Molina JA, Elliott RJ, Navia B, Lanza VF, Vallejo A, Osman M, Dronda F, Budree S, Zamora J, Gutiérrez C, Manzano M, Vivancos MJ, Ron R, Martínez-Sanz J, Herrera S, Ansa U, Moya A, Moreno S. Fecal microbiota transplantation in HIV: A pilot placebo-controlled study. Nat Commun. 2021 Feb 18;12(1):1139. doi: 10.1038/s41467-021-21472-1. PMID: 33602945.

Screening of faecal microbiota transplant donors during the COVID-19 outbreak: suggestions for urgent updates from an international expert panel

Ianiro, G., Mullish, B., Kelly, C., Sokol, H., Kassam, Z., & Ng, S. et al. (2020). Screening of faecal microbiota transplant donors during the COVID-19 outbreak: suggestions for urgent updates from an international expert panel. The Lancet Gastroenterology & Hepatology. doi:10.1016/s2468-1253(20)30082-0

The impact of gastrointestinal dysmotility on the aerodigestive microbiome of pediatric lung transplant recipients

Lötstedt B, Boyer D, Visner G, Freiberger D, Lurie M, Kane M, DiFilippo C, Lundeberg J, Narvaez-Rivas M, Setchell K, Alm E, Rosen R. The impact of gastrointestinal dysmotility on the aerodigestive microbiome of pediatric lung transplant recipients. J Heart Lung Transplant. 2020 Dec 5:S1053-2498(20)31860-X. doi: 10.1016/j.healun.2020.11.013. Epub ahead of print. PMID: 33349521.

Triclosan has a robust, yet reversible impact on human gut microbial composition in vitro

Mahalak, K., Firrman, J., Lee, J., Bittinger, K., Nunez, A., Mattei, L., Zhang, H., Fett, B., Bobokalonov, J., Arango-Argoty, G., Zhang, G., Zhang, G., Liu, Lin. (2020) Triclosan has a robust, yet reversible impact on human gut microbial composition in vitro. PLONE ONE. 15(6): e0234046. https://doi.org/10.1371/journal. pone.0234046